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| Single Cell Genome Sequencing Market |
Sngle cell genome sequencing involves isolating single cells and analyzing the genome of each cell separately. It has gained prominence in recent years due to its ability to study cellular heterogeneity at an unprecedented resolution. Single cell sequencing helps to identify rare cell types and trace cell lineage decisions during development, disease onset and response to therapy. It has wide application in cancer research for understanding tumor evolution, detecting circulating tumor cells and deciphering intra-tumor heterogeneity. Other key applications of single cell sequencing include neurobiology, immunology and stem cell research.
The Global Single Cell Genome Sequencing Market is estimated to be valued at US$ 2.63 Bn in 2024 and is expected to
exhibit a CAGR of 3.9% over the
forecast period from 2024 to 2030.
Key Takeaways
Key players operating in the single cell genome sequencing are Logitech
International SA, Microsoft Corporation, Datadesk Technologies, Inc., Fentek
Industries Inc., Adesso AG, Shenzhen V4 Electronic Co., Ltd., Fellowes Limited,
Kinesis Corporation, Gold Touch Enterprise Inc., and Posturite UK Ltd. Rapidly
declining costs of sequencing is encouraging adoption by research institutes
and pharmaceutical companies. Technological advancements have enabled analysis
of thousands of cells in parallel, improving throughput and discovery
potential.
Major companies are focusing on geographical expansion to tap growth
opportunities in emerging markets. For instance, 10x Genomics recently opened
facilities in Belgium and China. Fluigent launched its microfluidic platform in
India in 2020. Such initiatives will help make single cell analyses accessible
to global research communities.
Rising cancer incidence, increasing R&D investments in immunology and
growing stem cell therapies market are expected to drive the demand for single
cell genome sequencing. Growing application scope in prenatal diagnosis and
non-invasive prenatal testing using cell-free DNA analysis from maternal blood
is opening new avenues.
Market Drivers
Declining cost of sequencing: Continuous reductions in the cost of sequencing
equipment and consumables is increasing the affordability of single cell
sequencing experiments. This key driver is expected to boost adoption in
research as well as clinical settings.
Technological advances: Introduction of microfluidic platforms, droplet-based
workflows and automation solutions have enhanced throughput, reproducibility
and analysis potential. This is a major factor contributing to market growth.
Market Restrain
Complexity of workflow: Isolating viable single cells and preparing
representative sequencing libraries requires specialized expertise and
infrastructure. Technical challenges related to whole genome amplification add
to the complexity. This restrain limits widespread adoption.
Lack of standardization: Absence of standardized protocols and quality control
measures hinders multi-center clinical trials and collaborative research
involving data from different sources. It poses challenges for translation into
clinical practice.
Segment Analysis
Single Cell
Genome Sequencing Market Trends there are mainly two types of single
cell sequencing instruments: Next Generation Sequencing and PCR. Next
Generation Sequencing dominates the market as it provides high-throughput
analysis and sequencing data quickly at a reduced cost. Single cell RNA
sequencing and whole genome sequencing are the major applications of single
cell genome sequencing techniques. Single cell RNA sequencing is currently the
dominating sub-segment as it allows profiling gene expression for thousands of
cells simultaneously and helps in understanding cell heterogeneity.
Global Analysis
In terms of regional analysis, North America is dominating the single cell
genome sequencing market owing to high adoption of technologically advanced
products, rising R&D investments in life science research and availability
of favorable funding from private and public organizations in the US and
Canada. Asia Pacific is forecasted to grow at the fastest rate during the
forecast period owing to increasing healthcare expenditures, rising incidences
of chronic diseases, growing geriatric population and increasing awareness
about personalized medicine in countries such as Japan, China and India.
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