In order to make the treatment of osteoarthritis more effective, it is crucial to improve the quality of the cartilage. Although this therapy does not have any immediate or long-term benefits, it is believed to improve pain and function in patients suffering from arthritis. However, it should be noted that mesenchymal stem cells cannot regenerate cartilage. It may not work as well on people suffering from degenerative arthritis.
Along with enhancing cartilage regeneration, the local milieu plays an important role in determining the effectiveness of the therapy. Studies have shown that factors such as bone morphogenetic protein (BMP) and fibroblast growth factor 18 (FGF18) enhance the outcome of the treatment. These factors have been demonstrated to enhance the effectiveness of cartilage repair. These factors may help doctors improve the quality of life for their patients with arthritis. Currently, cell therapies for cartilage repair involve surgical debridement, a biopsy of healthy cartilage, and implanting these cultured cells several weeks later. The wait period can be quite lengthy, and can cause significant stress for patients. Moreover, the resected tissue is processed into chondrons and mixed with allogeneic stem cells. These chondrons are then used as the implants in the patient.
The growing geriatric population is an important factor driving the demand for stem cell cartilage regeneration therapy. The growing aging population in the United States is prone to a wide range of degenerative diseases, including osteoarthritis and arthritis. Researchers believe that the combination of stem cell mediated therapy and gene transfer may be a promising option for regenerating damaged cartilage. If successful, the procedure will improve the quality of life for sufferers and reduce the pain associated with the disease. Stem cell cartilage regeneration therapy has become a promising treatment for osteoarthritis disease. Researches have conducted numerous animal models to mimic the regeneration process in humans, and the results have been encouraging. A reputable clinic will be able to successfully regenerate damaged cartilage in the patient, which is a major drawback of the treatment. Recently in August 2020, scientists at the Stanford University School of Medicine discovered a new way for regenerating the cartilage found in joints that eases movements in bones.
0 Comments